Yes.
I started by joining a thriving instance and watching the Local and Federated feeds.
Then I started following hashtags.
Then I found people posting things I liked and started following people.
It took time, months, but I have a very active feed and about two dozen Lists for when I just want to see a certain type of Toot.
Things I miss:
- The artists I followed on Instagram. I'm now supporting two of them via Patreon or Liberapay because they also post here.
- The onslaught of dank memes.